RSS Stem Cells News — ScienceDaily

  • Phenogenetic map created for stem cells models of neurological diseases October 19, 2017
    In an effort to better understand neurological diseases like Alzheimer's, Parkinson's and ALS -- and develop new ways to treat them -- researchers have performed the first meta-analysis of all induced pluripotent stem cell models for neurological and neurodegenerative diseases, and created an atlas of how cell characteristics are linked to their genotype.
  • Inflamed support cells appear to contribute to some kinds of autism October 18, 2017
    Modeling the interplay between neurons and astrocytes derived from children with Autism Spectrum Disorder (ASD), researchers say innate inflammation in the latter appears to contribute to neuronal dysfunction in at least some forms of the disease.
  • Inflammation trains the skin to heal faster October 18, 2017
    Stem cells in the skin remember an injury, helping them close recurring wounds faster, researchers have found. The discovery could advance research and treatment of psoriasis and other inflammatory diseases.
  • New findings explain how UV rays trigger skin cancer October 18, 2017
    Melanoma, a cancer of skin pigment cells called melanocytes, will strike an estimated 87,110 people in the US in 2017, according to the Centers for Disease Control and Prevention. A fraction of those melanomas come from pre-existing moles, but the majority of them come from sources unknown -- until now.
  • Saving hearts after heart attacks: Overexpression of a gene enhances repair of dead muscle October 17, 2017
    Biomedical engineers report a significant advance in efforts to repair a damaged heart after a heart attack, using grafted heart-muscle cells to create a repair patch. The key was overexpressing a gene that activates the cell-cycle of the grafted muscle cells, so they grow and divide more than control grafted cells.
  • Bolstering fat cells offers potential new leukemia treatment October 16, 2017
    Killing cancer cells indirectly by powering up fat cells in the bone marrow could help acute myeloid leukemia patients, says a new study. Researchers found that boosting adipocytes, or fat cells, located in the bone morrow suppressed cancerous leukemia cells but -- in a surprise to the research team -- also induced the regeneration of […]
  • 3D packaging of DNA regulates cell identity October 12, 2017
    The ability of a stem cell to differentiate into cardiac muscle (and by extension other cell types) depends on what portions of the genome are available for activation, which is controlled by the location of DNA in a cell's nucleus, new research suggests.
  • Scientists pinpoint surprising origin of melanoma October 12, 2017
    A team of researchers has tracked down the cellular origin of cutaneous melanoma, the deadliest form of skin cancer. The team was surprised to observe that these very aggressive tumors arise from mature, pigment-producing cells called melanocytes. As melanoma develops, these cells are eventually reprogrammed, lose their differentiated features and become invasive, migratory cancer cells. […]
  • New type of stem cell line produced offers expanded potential for research and treatments October 11, 2017
    Researchers have created expanded potential stem cells (EPSCs) in mice, for the first time, that have a greater potential for development than current stem cell lines. These stem cells have the features of the very first cells in the developing embryo, and can develop into any type of cell.
  • Growing human brain cells in the lab October 10, 2017
    A cost-effective technology has been developed to produce large quantities of human brain cells in two simple steps. By surmounting major challenges in human neuron-based drug discovery, researchers believe this technique will be adopted widely in both basic science and industry.