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A better understanding of lipids cellular metabolism may have clinical applications with regenerative medicine in the future. A recent article published in the journal Nature Medicine investigates an interesting question. Why do many older people struggle to keep from gaining excess weight? This longitudinal study took place over a 13-year period and they studied the fat cells of 54 men and 41 women who had gastric bypass type surgery. They found that over time the rate of lipid turnover in these individuals slowed up. This decreasing rate of processing fat appeared to be an independent variable on a cellular level. It also suggested that one way to increase lipid metabolism is regular exercise.