Stem Cell Delivery Technique for Spinal Cord Regenerative Medicine

Significant research is underway in Regenerative Medicine to use neural stem cells or neural precursor cells to repair spinal cord injuries or diseases. One of the issues to address has been the delivery method to get these stem cells and growth factors into the spinal cord. Stem cells are able to generate into different types of functional cells. Platelet Rich Plasma (PRP) is a method to inject growth factors and draw in Stem Cells. One of the differential cells down the line are neural precursor cells. Stem cells differentiate into other types of cells in part because of the environment or types of cells that are surrounding them.

There is an inherent risk when injecting stem cells into or around the spinal cord as the needle itself can cause damage to the spinal cord or cause bleeding in the area. Researchers at the University of California San Diego School of Medicine have been conducting new delivery techniques play stem cells in and around injured spinal cords. They have been experimenting on mice trying to find a precise delivery method for the spinal stem cells which minimize the risk of spinal cord injury. They have developed a new technique which is less invasive, where they inject the cells into a tiny space just above the spinal cord. This anatomical space is called the spinal subpial space. When neural stem cells are placed in this area they are able to migrate into the damaged or diseased areas and take on the regenerative properties of the cells around them with the goal to become functional healthy neural cells. Further research is planned on different animal models with anatomy resembling human structures.

Martin Marsala, Kota Kamizato, Takahiro Tadokoro, Michael Navarro, Stefan Juhas, Jana Juhasova, Silvia Marsala, Hana Studenovska, Vladimir Proks, Tom Hazel, Karl Johe, Manabu Kakinohana, Shawn Driscoll, Thomas Glenn, Samuel Pfaff, Joseph Ciacci. Spinal parenchymal occupation by neural stem cells after subpial delivery in adult immunodeficient ratsSTEM CELLS Translational Medicine, 2019; 9 (2): 177 DOI: 10.1002/sctm.19-0156

Cosmetic Gift Certificates

Are you looking for last minute gift ideas? Pamper them and yourself with cosmetic gift certificates. Through the month of December purchase a gift certificate for micro-needling or a Botox treatment and get a coupon to use for yourself for 15% off your Botox or micro-needling treatment. Micro-needling, also called collagen induction therapy, can have results which improve skin texture and help reduce fine lines and wrinkles. Botox is a very common cosmetic procedure that helps relax muscles and soften wrinkles and creases around the face. Contact us to purchase your gift certificate and receive your 15% off coupon. Restrictions apply. Happy Holidays.

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Botox Cosmetic Day

Botox cosmetic to help reduce fine lines and wrinkles is a very popular treatment nationally and at DaVinci Med Spa. Today is botox cosmetic day. To help celebrate we are offering a special for $125 Botox gift certificate for only $100. Contact us to redeem this offer and schedule a consultation. Conditions apply. #BotoxCosmeticDay

Lipid turnover rates and aging insight may help with regenerative medicine

A better understanding of lipids cellular metabolism may have clinical applications with regenerative medicine in the future. A recent article published in the journal Nature Medicine investigates an interesting question. Why do many older people struggle to keep from gaining excess weight? This longitudinal study took place over a 13-year period and they studied the fat cells of 54 men and 41 women who had gastric bypass type surgery. They found that over time the rate of lipid turnover in these individuals slowed up. This decreasing rate of processing fat appeared to be an independent variable on a cellular level. It also suggested that one way to increase lipid metabolism is regular exercise.

Forehead Wrinkle Reduction with Botox

We all love to laugh, smile and show happy excitement. Many of us want to do this with a smooth clear forehead when we face the world and the mirror. Botox is a simple and effective method to reduce unwanted forehead wrinkles and lines. At DaVinci Med Spa we pride ourselves in great results with happy clients who face the world with a beautiful smile. Here is it before and after from one of our patients who took some selfies. This is some of the Botox work we do at DaVinci Med Spa. We love it when our clients are so excited they want to share their results with the world.

Botox, DaVinci Med Spa

Regenerative Medicine and Human Neural Networks

Regenerative medicine has reached another milestone. Scientist from the University of California San Diego have demonstrated neural network activity which mimics early human brain activity. Using pluripotent stem cells the researchers were able to place them in an environment which promoted the development of brain tissue. The development progressed far enough to actually begin demonstrating neural network activity. These were observed using EEG technology. While these group of neural cells are only about the size of a pea, this is a huge development in using regenerative medicine to create human brain tissue.

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Exercise and well being

The physical health benefits of exercise are widely understood and agreed upon. The benefits of exercise for a healthy mind is also commonly understood. A new research study from the journal Global Advances in Health and Medicine from this year have demonstrated this healthy benefit for the mind through scientific research. Practitioners at inpatient psychiatric facilities acquired baseline reporting for their patients feelings. They measured levels of anger,  anxiety, depression, self-esteem and overall moods. They had roughly 100 patients exercise routinely in a gym for 30 minutes a day and then re-evaluated there in patients experiences. They found a significant reduction in negative feelings and an increase in their feelings of well-being. Overall patients were very pleased with structural exercises and the doctors saw a decrease in the amount of time they needed to be in the hospital and hopefully a reduction in the medications that were needed. Checking with the physician before beginning an exercise program is an important part. Exercise is good for the body and the mind. Self esteem and feeling good about yourself are both very important.

self esteem well being
Botox Dr AJ Cummings DaVinci Med Spa

Botox Results

Our clients love the results they get with Botox to soften their wrinkles. We are delighted when they share those results with us through selfies! She did not like the forehead lines and “11” lines she was getting between her eyebrows. After a consultation at DaVinci Med Spa, she got her Botox treatment and the wrinkles softened.

Botox Dr AJ Cummings forehead and 11 lines wrinkles treatment DaVinci Med Spa

Call us for a consultation and let’s see what we can do for your wrinkles.

Chicago Aesthetics Conference

Dr. AJ Cummings attended a medical aesthetics conference in Chicago last weekend. The latest techniques for fillers and Botox were reviewed as well as Skin Rejuvenation with laser therapy. Valuable time was also spent with colleagues discussing some of the many clinical results experienced with different PRP uses. Specifically micro-needling with platelet-rich plasma which DaVinci Medical has been offering as anesthetics option for skin rejuvenation.

Hair restoration research with medications

Cosmetic hair restoration is an issue that many men and women suffer with with male pattern baldness and thinning hair. A group of researchers at the University of Manchester published a study showing how the side effects of some medications can actually be used to help stimulate hair growth. A drug that has been around since the 1980’s called Cyclosporine A had a side effect of patients having hair growth. The researchers discovered that the drug has in it an inhibitory mechanism that stops the body from using a certain protein that inhibits the growth of hair cells. The researchers used donated human hair follicles and found they promoted the human hair growth in the laboratory. Further research is needed.

Minimally invasive procedures which promote blood circulation in the scalp and stimulate growth factors include micro-needling with or without platelet rich plasma PRP.

  1. Nathan J. Hawkshaw, Jonathan A. Hardman, Iain S. Haslam, Asim Shahmalak, Amos Gilhar, Xinhong Lim, Ralf Paus. Identifying novel strategies for treating human hair loss disorders: Cyclosporine A suppresses the Wnt inhibitor, SFRP1, in the dermal papilla of human scalp hair folliclesPLOS Biology, 2018; 16 (5): e2003705 DOI: 10.1371/journal.pbio.2003705
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