RSS Stem Cells News — ScienceDaily

  • 'Inflamm-aging' causes loss of bone healing ability in the elderly March 18, 2019
    Increases in chronic inflammation -- not the passage of time -- is the main reason why injured bones do not heal as well with age.
  • Oscillation in muscle tissue March 15, 2019
    When a muscle grows or a muscle injury heals, some of the stem cells develop into new muscle cells. A research team has now described how this process is regulated by two proteins produced in an oscillatory manner.
  • Cell therapy could replace need for kidney transplants March 14, 2019
    Scientists are working on a promising approach for treatment of chronic kidney disease -- regeneration of damaged tissues using therapeutic cells.
  • Hematopoietic stem cells: Making blood thicker than water March 13, 2019
    A team revealed that Ragnase-1 is a key regulator of the self-renewal and differentiation of hematopoietic stem and progenitor cells. Knockout of this gene in mice resulted in aberrant blood cell composition and hematopoiesis, and caused health-related outcomes such as low hemoglobin, enlarged spleen, and early death. This insight into blood cell homeostasis and differentiation […]
  • Genetically encoded sensor isolates hidden leukemic stem cells March 12, 2019
    Researchers have devised a novel biosensor that can isolate and target leukemic stem cells. It can provide a prototype for precision oncology efforts to target patient-specific cells to fight the deadly disease.
  • Mini kidneys from urine cells March 4, 2019
    Scientists have successfully created kidney organoids from urine cells. This could lead to a wide range of new treatments that are less onerous for kidney patients.
  • Discovery of the genetic 'conductor' of brain stem cells March 4, 2019
    Our brain comprises 85 billion nerve cells and just as many so-called glial cells. But what decides when and how many of them become neurons or glial cells? A new study has shown how the Foxg1 gene plays a fundamental role in piloting the differentiation of stem cells, guaranteeing that neurons and glial cells are […]
  • Scientists rejuvenate stem cells in the aging brain of mice March 1, 2019
    Scientists have been able to rejuvenate stem cells in the brain of aging mice. The revitalized stem cells improve the regeneration of injured or diseased areas in the brain of old mice. The researchers expect that their approach will provide fresh impetus in regenerative medicine and facilitate the development of stem cell therapies.
  • Nicotine may harm human embryos at the single-cell level February 28, 2019
    Nicotine induces widespread adverse effects on human embryonic development at the level of individual cells, researchers report. Single-cell RNA sequencing of human embryonic stem cell (hESC)-derived embryoid bodies revealed that three weeks of nicotine exposure disrupts cell-to-cell communication, decreases cell survival, and alters the expression of genes that regulate critical functions such as heart muscle-cell […]
  • Turning them on, turning them off -- how to control stem cells February 28, 2019
    Scientists have identified how a mutant gene in fish is involved in controlling stem cells.