RSS Stem Cells News — ScienceDaily

  • Suntanner, heal thyself: Exosome therapy may enable better repair of sun, age-damaged skin September 19, 2019
    In a proof-of-concept study, researchers have shown that exosomes harvested from human skin cells are more effective at repairing sun-damaged skin cells in mice than popular retinol or stem cell-based treatments currently in use. Additionally, the nanometer-sized exosomes can be delivered to the target cells via needle-free injections.
  • Gene editing enables researchers to correct mutation in muscle stem cells in DMD model September 17, 2019
    Duchenne muscular dystrophy (DMD) is a rare but devastating genetic disorder that causes muscle loss and physical impairments. Researchers have shown in a mouse study that the powerful gene editing technique known as CRISPR may provide the means for lifelong correction of the genetic mutation responsible for the disorder.
  • Alzheimer's disease risk gene APOE4 impairs function of brain immune cells September 16, 2019
    A study carried out with a new human stem cell-derived model reveals that the most prevalent genetic risk factor of Alzheimer's disease (AD), apolipoprotein E4 (APOE4), impairs the function of human brain immune cells, microglia. These findings pave the way for new, effective treatment approaches for AD.
  • Stem cell researchers reactivate 'back-up genes' in the lab September 12, 2019
    Scientists have unraveled parts of a mechanism that may one day help to treat Rett syndrome and other genetic disorders linked to the X chromosome.
  • Infant with deadly leukemia saved by drug for adult liver cancer September 12, 2019
    Doctors have successfully treated an infant with a rare childhood leukemia using a targeted therapy approved for adults with inoperable liver cancer and advanced kidney cancer. The decision to use the drug, sorafenib, was made after pathologists identified a unique mutation of two genes being fused together instead of on separate chromosomes.
  • A diabetes drug promotes brain repair -- but it only works in females September 11, 2019
    Study finds that the diabetes drug metformin, known to promote brain repair, can also help restore cognitive function in adult mice but only in females and in a way that is dependent on the sex hormone estradiol.
  • A swifter way towards 3D-printed organs September 6, 2019
    Twenty people die waiting for an organ transplant every day in the US, but lab-grown organs so far lack the cellular density, vasculature, and functions required to make them viable replacements. The new SWIFT method solves those problems by 3D printing vascular channel networks directly into living organ building blocks, enabling the creation of larger […]
  • The neurobiological mechanisms behind schizophrenia may depend on gender September 3, 2019
    The neurobiological pathophysiology of schizophrenia differs significantly between males and females, according to a new study. The findings suggest a possible need for more sex-specific treatments for schizophrenia. The study was the first to identify a number of sex-specific genes related to schizophrenia using neurons derived from induced pluripotent stem cells.
  • Enzyme known for promoting cancer found to also protect healthy cells September 2, 2019
    New research reveals a new role for the enzyme telomerase, which scientists thought was turned off in most normal adult cells, except in cancerous tumors where it promotes unlimited cell division. The researchers discovered that as normal, healthy adult cells approach cell-death, they produce a burst of telomerase that prevents malignancies and softens the final […]
  • Brain waves detected in mini-brains grown in a dish August 29, 2019
    Scientists have created miniature brains from stem cells that developed functional neural networks. Despite being a million times smaller than human brains, these lab-grown brains are the first observed to produce brain waves that resemble those of preterm babies.