RSS Stem Cells News — ScienceDaily

  • Lab-grown beating heart cells identify potential drug to prevent COVID-19-related heart damage August 5, 2021
    Scientists have grown beating heart cells in the lab and shown how they are vulnerable to SARS-CoV-2 infection. In a new study, they used this system to show that an experimental peptide drug called DX600 can prevent the virus entering the heart cells.
  • Researchers discover key stem cell dormancy mechanism which could help unlock future cancer treatments August 3, 2021
    Researchers have made new findings which provide a broader understanding of how dormant hematopoietic stem cells are activated and could pave the way towards therapeutic treatments for a number of cancers.
  • Toxicity testing on the placenta and embryo July 21, 2021
    Researchers have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.
  • New spray could someday help heal damage after a heart attack July 14, 2021
    Heart attack, or myocardial infarction, is one of the leading causes of death worldwide. Although modern surgical techniques, diagnostics and medications have greatly improved early survival from these events, many patients struggle with the long-term effects of permanently damaged tissue, and the 5-year mortality rate remains high. Now, researchers have developed a minimally invasive exosome […]
  • A common ancestor for cells involved in hearing and touch July 12, 2021
    There are striking similarities in the development of two types of specialized sensory cells: the so-called 'hair cells' that receive sound vibrations in the inner ear, and the Merkel cells that sense light touch at the surface of the skin. These developmental similarities are a legacy of shared evolutionary history.
  • Sensing 'junk' RNA after chemotherapy enhances blood regeneration July 12, 2021
    Scientists reveal that during hematopoietic regeneration, RNA expressed from a part of the genome considered 'junk DNA' is used by hematopoietic stem cells to get activated and proliferate. The study shows that these so-called transposable elements make RNA after chemotherapy and activate an immune receptor which induces inflammatory signals enhancing hematopoietic stem cell cycling and […]
  • Stem cells can use same method as plants and insects to protect against viruses July 8, 2021
    Researchers have found a vital mechanism, previously thought to have disappeared as mammals evolved, that helps protect mammalian stem cells from RNA viruses such as SARS-CoV-2 and Zika virus. The scientists suggest this could one day be exploited in the development of new antiviral treatments.
  • Muscles retain positional memory from fetal life July 6, 2021
    Muscles and the resident stem cells (satellite cells) responsible for muscle regeneration retain memory of their location in the body. This positional memory was found to be based on the expression pattern of the homeobox (Hox) gene cluster, which is responsible for shaping the body during fetal life. These findings are expected to provide clues […]
  • Uncovering the genetic mechanism behind Rett syndrome July 2, 2021
    Researchers found that the main gene that causes Rett syndrome, MeCP2, controls the differentiation pattern of neural stem cells through the microRNA miR-199a. Dysfunction in MeCP2 or miR-199a cause neural stem cells to produce more astrocytes than neurons. Furthermore, the researchers found that miR-199a mediates the production of Smad1, a downstream transcription factor of bone […]
  • Human stem cells enable model to test drug impact on brain's blood barrier June 30, 2021
    Using an experimental model to simulate the blood-brain barrier, scientists reported in unprecedented detail how antioxidants protect the brain from inflammation caused by such neurodegenerative diseases as Alzheimer's and Parkinson's.